The Relation Antibody and Protection after Foot-and-mouth Disease Vaccination Cannot Be Standardised
نویسندگان
چکیده
Many studies have been performed into the relation antibody response and protection after footand-mouth disease (FMD) vaccination (Black et al. 1984; Pay et al. 1987; Pay et al. 1992). In every study a correlation was observed with the antibodies induced by the vaccine used in the study and protection observed after challenge. In the studies the methodology was never the same, e.g. the type of cells used in the virus neutralisation test (VNT), some studies were using ELISA and the statistical analysis. For countries not in the position to perform challenge experiments a standardised relation between antibody response after FMD vaccination and protection would be very useful. In the current study we try to standardise antibody level detection for FMD type O Manisa in two different ways, first by using a standardised commercial type PrioCHECK® FMDV Type O ELISA and secondly by inclusion of a standard 4 week post vaccination serum from a cow vaccinated with Cedivac® O Manisa FMD vaccine in both the ELISA and the VNT.
منابع مشابه
Neutralizing Antibody Response in Cattle Following Vaccination against Foot-and-Mouth Disease
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